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目的探讨霉菌性食管炎患者的发病诱因以及发病特点。方法对2006年1月到2011年6月在我院进行内镜检查确认的霉菌性食管炎患者共26例的临床资料进行回顾性分析。结果确认轻度感染6例,中度感染13例,重度感染7例。患者同时伴有其他肠胃疾病为:胃炎8例,消化性溃疡4例,胃炎伴胃溃疡4例,反流性食管炎3例,食管静脉曲张2例,胃癌3例。患者服用氟康唑或制霉菌素1～2周后,23名患者痊愈,另有3名患者因其他原因转到省级医院治疗,判定治愈率为88.5%。结论霉菌性食管炎近年来检出率较高,医务工作人员在患者患有其他疾病时应尽量减少抗生素或者强抑酸剂的使用,同时患者本身患有肠胃疾病时要尽早治疗,以避免霉菌的感染。
Objective To investigate the pathogenesis and incidence of fungal esophagitis in patients. Methods The clinical data of 26 patients with fungal esophagitis confirmed by endoscopy in our hospital from January 2006 to June 2011 were analyzed retrospectively. The results confirmed mild infection in 6 cases, moderate infection in 13 cases, severe infection in 7 cases. Patients accompanied by other gastrointestinal diseases are: 8 cases of gastritis, peptic ulcer in 4 cases, gastritis with gastric ulcer in 4 cases, reflux esophagitis in 3 cases, esophageal varices in 2 cases, gastric cancer in 3 cases. After taking fluconazole or nystatin for 1 to 2 weeks, 23 patients recovered and another 3 patients were transferred to provincial hospital for other reasons. The cure rate was 88.5%. Conclusion The incidence of fungal esophagitis is high in recent years. Medical staff should try their best to reduce the use of antibiotics or strong acid-suppressing agents in patients with other diseases, and treat patients with gastrointestinal diseases as soon as possible so as to avoid Mold infection.