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目的探讨原发性高血压病(EH)血压变异性(BPV)的临床意义。方法对45例EH患者和40例健康者(对照组)进行24h动态血压监测(ABPM),以测得的各时间段血压标准差(SD)作为BPV指标。结果 EH组血压变异性明显大于对照组,Ⅱ、Ⅲ期EH患者血压变异性明显大于Ⅰ期EH患者;EH患者血压变异性随血压水平的增加而逐渐增大。结论血压变异增大是高血压患者的一个重要临床特征,血压变异增大与靶器官损害有关。
Objective To investigate the clinical significance of blood pressure variability (BPV) in essential hypertension (EH). Methods Forty-five patients with EH and 40 healthy controls (control group) underwent 24-hour ambulatory blood pressure monitoring (ABPM). The standard deviation (SD) of blood pressure at each time period was taken as the BPV index. Results The variability of blood pressure in EH group was significantly higher than that in control group. The variability of blood pressure in EH patients in stage Ⅱ and Ⅲ was significantly higher than that in stage Ⅰ EH. The variability of blood pressure in EH patients increased with the increase of blood pressure. Conclusion Increased blood pressure variability is an important clinical feature in patients with hypertension. Increased blood pressure variability is associated with damage to target organs.