我县自1981年起发生家鼠型出血热流行,其流行特征和临床表现似乎与野鼠型出血热无严格区别。但从对人群普遍易感且隐性感染率远高于野鼠型[1]看,似乎家鼠型病毒具有广谱的抗原性和高免疫源性。为此我们进行从家鼠型出血热病人体内直接分离人源病毒株工作,以期获得家鼠型人源毒 Myxoplasma haemorrhagic fever occurs in our county since 1981, and its prevalence and clinical manifestations do not appear to be strictly different from wild-type haemorrhagic fever. However, from the general population susceptibility and latent infection rate is much higher than the wild mouse type [1], it seems that the domestic mouse virus has a broad spectrum of antigenicity and high immunogenicity. To this end, we conducted a direct isolation of human virus strains from domestic murine hemorrhagic fever patients in order to obtain domestic mouse-type human toxin