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英国人的布氏杆菌病(以下简称布病)系由流产布氏杆菌所致。急性和慢性两型布病本质上均是一种病菌在细胞内寄生的疾病,因此需要通过应用能穿透到细胞内的药物,或使药物在细胞外维持较长时间高浓度来清除细胞内的病原体才能疗效良好。四环素族抗菌素已应用多年,而且是治疗布病的有效药物。本文作者曾用四环素2g/d,4周为一疗程,共3疗程,每个疗程间隔4周,治疗30余例急性布病,未见复发。1976年 Farrel 等比较了布氏杆菌对四环素族药物的体外敏感度:去甲金霉素、强力霉素、赖氨四环
British Brucellosis (hereinafter referred to as brucellosis) caused by abortion Brucella. Both acute and chronic brucellosis are essentially a disease of parasites of pathogens in the cell and therefore need to be cleared by the use of drugs that penetrate the cells or by leaving the drug in the cell for longer periods of time at high concentrations The pathogen can be effective. Tetracycline antibiotics have been used for many years and are effective medicines for the treatment of brucellosis. The authors used tetracycline 2g / d, 4 weeks for a course of treatment, a total of 3 courses, each treatment interval of 4 weeks, the treatment of more than 30 cases of acute brucellosis, no recurrence. In 1976, Farrel et al compared the in vitro susceptibilities of brucellosis to tetracycline drugs: naringcium, doxycycline,