论文部分内容阅读
目的:分析湖北省荆门地区2011年药品不良反应(ADR)发生特点,促进临床合理用药。方法:查阅荆门地区2011年各报告单位上报国家药品不良反应监测中心ADR报告1 166份,分别统计报告单位、患者年龄、不良反应类型、药品种类、结果评价等项目并分析。结果:1 166例中自医疗机构的报告占98.8%;ADR患者男女比例相当;静滴引起的ADR占86.7%;抗感染药物引起的ADR占59.1%,其中以头孢菌素类发生的ADR最多;消化系统的ADR最多,占33.2%;评价结果为可能的ADR最多,占44.5%;百万人口ADR的发生率为393例。结论:各报告单位要不断提高报告质量,保证临床用药安全、有效。
Objective: To analyze the characteristics of adverse drug reaction (ADR) in Jingmen area of Hubei province in 2011, and to promote the clinical rational use of drugs. Methods: To find out the 1,166 ADR cases reported by all the reporting units in the national drug adverse reaction monitoring center in 2011 in Jingmen area, and to analyze and analyze the units, patient ages, types of adverse reactions, types of drugs, results evaluation and so on. RESULTS: The reports of 1 166 cases from medical institutions accounted for 98.8%. The ADR patients had the same ratio of men and women. The ADR caused by intravenous drip was 86.7%. The ADR caused by anti-infective drugs accounted for 59.1%, of which the most ADR was cephalosporin ; The digestive system had the highest ADR, accounting for 33.2%; the most likely ADR was assessed as 44.5%; the incidence of ADR per million population was 393 cases. Conclusion: All reporting units should continuously improve the quality of reports and ensure the safety and effectiveness of clinical medication.