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白假丝酵母是目前最常见的条件致病菌。从临床念珠菌感染病例分离株的耐药性进行流行病研究， 可以为指导临床用药提供参考。对由妇科念珠菌性阴道炎患者的外阴分泌物分离纯化得到的９０株假丝酵母 进行了系统鉴定并测定了对 ＭＣＺ， ＫＣＺ和 ＦＣＺ ３种药物的 ＭＩＣ，分析了菌群变化及 ＭＩＣ分布。结果显示，非 白假丝酵母所占比例（４０．０％）明显上升，成为主要条件致病菌，而白假丝酵母所占比例仅为３７．７％，已明显下 降；同时亦显示不同种类的假丝酵母对上述３种抗真菌药物的敏感性也不同。这种菌群变迁可能与近年来抗 真菌药物的广泛应用有关。
Candida albicans is currently the most common conditions of pathogens. Epidemiological studies on the drug resistance of clinical isolates from clinical Candida infections may provide a reference for guiding clinical drug use. 90 strains of Candida isolated from vulvovaginal secretions of gynecological Candida vaginitis were systematically identified and the MICs of MCZ, KCZ and FCZ were determined. The changes of bacterial population and MIC distribution were analyzed. The results showed that the proportion of non-Candida albicans (40.0%) increased significantly, becoming the main conditions of pathogens, and Candida albicans accounted for only 37.7%, has decreased significantly; also showed different Candida species of these three kinds of anti-fungal drug sensitivity is also different. This change in flora may be related to the wide use of antifungal agents in recent years.