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目的探讨泮托拉唑治疗消化性溃疡合并出血的临床疗效。方法 60例消化性溃疡合并出血患者,随机分为观察组和对照组,各30例。观察组给予泮托拉唑治疗,对照组给予奥美拉唑治疗,比较两组治疗效果及不良反应情况。结果观察组总有效率为93.3%,对照组总有效率为90.0%;两组比较差异无统计学意义(P>0.05)。观察组不良反应发生率6.7%低于对照组的30.0%,差异有统计学意义(P<0.05)。结论泮托拉唑治疗消化性溃疡合并出血疗效显著,不良反应较少,值得借鉴。
Objective To investigate the clinical efficacy of Pantoprazole in the treatment of peptic ulcer combined with hemorrhage. Methods Sixty patients with peptic ulcer with hemorrhage were randomly divided into observation group and control group with 30 cases in each group. The observation group was treated with pantoprazole, while the control group was treated with omeprazole. The therapeutic effects and adverse reactions were compared between the two groups. Results The total effective rate was 93.3% in the observation group and 90.0% in the control group. There was no significant difference between the two groups (P> 0.05). The incidence of adverse reactions in the observation group was 6.7% lower than that in the control group (30.0%), the difference was statistically significant (P <0.05). Conclusion Pantoprazole treatment of peptic ulcer bleeding with significant effect, less adverse reactions, it is worth learning.