激素抵抗性肾病综合征在大多数患者中 ,可进展到终末期肾病。对于激素抵抗性肾病综合征以往常采用细胞毒药物或免疫抑制剂 ,使用此类药物 ,常因其毒副作用大 ,疗效差而受限。我们对我院 2 0 0 0年 8月～ 2 0 0 1年 3月住院患者应用甲基强的松龙冲击联合肾肝宁疗法治疗激素抵抗 Hormone-resistant nephrotic syndrome can progress to end-stage renal disease in most patients. For hormone-resistant nephrotic syndrome used to use cytotoxic drugs or immunosuppressive agents, the use of such drugs, often because of its toxic side effects, poor efficacy and limited. We hospitalized our hospital from August 2000 ~ March 2001 inpatients with methylprednisolone shock combined with neogunning treatment of hormone resistance