地中海贫血(Thalassemia,简称地贫)是一种常染色体缺陷导致的血液系统遗传性疾病,由于珠蛋白基因先天性突变或缺失而使珠蛋白链生成障碍,导致血红蛋白合成减少,最终引起溶血性贫血,α和β地贫是最常见、最重要的类型~([1])。本研究对地贫患儿体内铁代谢及红细胞系造血指标进行检测,旨在探讨不同基因型地贫患儿铁储存和红细胞系造血状况,为临床治疗提供依据。1资料与方法1.1对象选2013年1月至2015年12月在本院住 Thalassemia (Thalassemia) is a genetic hereditary disease of the hematological system caused by autosomal defects. Due to congenital mutations or deletions of the globin gene, the globin chain is impaired, leading to a decrease of hemoglobin synthesis and finally to hemolytic anemia , α and β thalassemia is the most common and important type ~ ([1]). In this study, iron metabolism in patients with thalassemia and hematopoietic index of erythrocyte hematopoiesis were detected in order to explore the iron storage and hematopoietic status of erythrocyte in children with thalassemia of different genotypes and to provide evidence for clinical treatment. 1 Materials and Methods 1.1 object selected January 2013 to December 2015 in our hospital