成纤维细胞生长因子20(FGF20)是成纤维细胞生长因子家族(FGFs)的成员之一。研究发现,FGF20具有广泛生物学活性,不仅在退行性神经系统疾病,如帕金森病中起着重要作用,还在组织修复,肿瘤发生、器官发育等方面具有重要的生物学功能。尽管作为重组蛋白药物的开发其功能和机制仍有待进一步研究,但FGF20所具备的生物学特性将会有非常广阔的研究领域和应用价值。 Fibroblast growth factor 20 (FGF20) is a member of the fibroblast growth factor family (FGFs). The study found that FGF20 has a wide range of biological activity, not only in degenerative diseases of the nervous system, such as Parkinson’s disease plays an important role, but also in tissue repair, tumorigenesis, organ development has important biological functions. Although its function and mechanism as a recombinant protein drug still need further study, the biological characteristics of FGF20 will have a very broad research field and application value.