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目的探讨性染色体异常和不孕不育的关系。方法采用外周血淋巴细胞染色体培养技术,G显带,显微镜下核型分析,计数20个核型,分析3个核型。嵌合型加数至50个核型。结果 70例性染色体异常核型中,数目异常50例,占异常核型的71.43%;结构异常8例,占11.43%;Y染色体形态异常9例,占12.86%;另外还有表型异常3例,占4.28%。结论性染色体异常是导致不孕不育的主要原因之一,有必要推广针对不孕不育和不良孕育史的家庭夫妻双方的染色体检查和婚前染色体检查。
Objective To explore the relationship between sex chromosome abnormalities and infertility. Methods Peripheral blood lymphocyte chromosome culture technique, G - banding, karyotype analysis under microscope, counting 20 karyotypes and analyzing 3 karyotypes. Chimeric Addition to 50 karyotypes. Results 70 cases of chromosomal abnormalities karyotype, the number of abnormal 50 cases, accounting for 71.43% of abnormal karyotype; structural abnormalities in 8 cases, accounting for 11.43%; Y chromosome abnormalities in 9 cases, accounting for 12.86%; in addition to phenotypic abnormalities 3 Cases, accounting for 4.28%. Conclusions Sexual chromosomal abnormality is one of the main causes of infertility. It is necessary to promote the chromosomal examination and premarital chromosome examination of both husband and wife in the history of infertility and poor fertility.