本文首次报告了 A 型肉毒毒素对面肌痉挛的治疗作用。毒素注射部位为眼周5个点,颊部2个点,每点注射 A 型肉毒毒素2.5单位(0.001微克/0.1毫升)。治疗后所有病人都感到面肌痉挛减轻,注射后12～48小时,平均30.5小时即获改善,持续4～6周,平均为12.2周。治疗并发症包括流泪、眼不能闭合、角膜暴露,睑外翻。这些不良反应是轻微的,暂时的,可在两周内 This article first reported the therapeutic effect of botulinum toxin A on hemifacial spasm. The site of toxin injection was 5 points on the ocular periphery and 2 points on the cheek. Each point was injected with 2.5 units of botulinum toxin type A (0.001 μg / 0.1 ml). After treatment, all patients felt hemifacial spasm reduced, 12-48 hours after injection, an average of 30.5 hours to be improved for 4 to 6 weeks, with an average of 12.2 weeks. Treatment complications include tearing, failure to close eyes, corneal exposure, eyelid eversion. These adverse reactions are mild, temporary, and can be within two weeks