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【目的】探讨高频超声在类风湿性关节炎（rheumatoid arthritis ，RA）膝关节病变中的诊断价值。【方法】收集 RA 患者40为观察组，40例健康志愿者为对照组，采用高频超声检测两组膝关节并比较分析。【结果】观察组采用高频超声检查发现76个关节异常，73个有不同程度的髌上囊积液，滑膜增厚76个 ，有49个探查到彩色血流信号。观察组Ⅱ～Ⅲ级滑膜增厚、髌上囊积液、关节滑膜内有血流信号所占的百分比分别为42．50％、38．75％、45．00％，而对照组均无。【结论】高频超声具有操作简单，价格低廉，重复性好等优点，对膝关节滑膜病变及髌上囊积液程度能做出准确判断，也能够清晰的显示滑膜内的血流信息，为临床诊断RA 提供依据。“,”Objective] To explore the application value of high frequency ultrasound in the diagnosis of rheumatoid arthritis (RA) of knee joint disease .[Methods] From March 2013 to February 2015 ,a total of 40 RA patients were selected as study group while another 40 healthy volunteers as control group .High frequen‐cy ultrasound was employed for examining and comparing knee joints for both groups .[Results] The study group revealed 76 joint abnormalities ,73 with varying degree of suprapatellar bursa effusion ,76 with synovial thickening and 49 with color flow signal .When study and control groups were compared ,the percentages ofⅡ ~ Ⅲ synovial thickening were 42 .50% versus 0 .00% ( P < 0 .05) , Ⅱ ~ Ⅲ patellar bursa effusion 38 .75%versus 0 .00% ( P < 0 .05) and flow signal within Ⅱ ~ Ⅲ synovial joint 45 .00% versus 0 .00% ( P < 0 .05) .[Conclusion] High frequency ultrasound offers the advantages of simple handling ,low cost and excellent re‐peatability so as to provide accurate blood flow information on synovium lesions and suprapatellar bursa effu ‐sion degree of knee joints .And it may provide rationales for clinical diagnosis of RA .