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目的探讨脑动静脉畸形(AVM)术后癫癎发生的危险因素。方法回顾性分析接受手术并有完整临床资料的脑动静脉畸形病例138例,以性别、年龄、主要症状、阳性体征、术前癫癎史、病变部位、畸形团大小、引流静脉、手术入路、术后水肿、病灶残留、手术次数、癫癎灶切除等13项可能的影响因素为自变量,设定术后发生癫癎为因变量,使用Logistic逐步回归分析研究相关的影响因素。结果术前癫癎史、病变部位、畸形团大小、引流静脉、术后水肿等5个因素是术后癫癎发生的危险因素。结论对脑动静脉畸形手术病人,应针对癫癎发生危险因素进行防治,以减少脑动静脉畸形术后癫癎的发生。
Objective To investigate the risk factors of epilepsy after cerebral arteriovenous malformation (AVM). Methods A retrospective analysis of 138 cases of cerebral arteriovenous malformations undergoing surgery with complete clinical data was performed on the basis of sex, age, major symptoms, positive signs, preoperative epilepsy, lesion, size of malformations, drainage veins, surgical approach , Postoperative edema, residual lesions, the number of operations, epileptogenic resection and other 13 possible influencing factors as independent variables, the setting of postoperative epilepsy as a dependent variable, the use of Logistic stepwise regression analysis to study the relevant factors. Results Preoperative epilepsy history, lesion location, malformation size, drainage veins, postoperative edema and other five factors are postoperative risk factors for epilepsy. Conclusion For patients with cerebral arteriovenous malformations, prevention and treatment of risk factors for epilepsy should be taken to reduce the incidence of epilepsy after cerebral arteriovenous malformations.