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目的:探讨米索前列醇在分娩中的特殊作用。方法:回顾分析我院2011年5月-2012年6月间收治住院的分娩产妇156例,均为足月待产孕妇,按入院先后分为米索组与催产素组,各78例,米索组运用米索前列醇片促进产程,催产素组运用催产素促进产程。结果:米索组总成功率为98.72%;催产素组总成功率为89.74%,两组疗效对比差异明显,P<0.05。无效9例,全部经剖腹术治疗。两组不良反应发生率对比,无明显差异,P>0.05;其余各项对比,均有显著差异,且米索组明显优于催产素组,P<0.05。由于两组的不良反应轻微,均未做特殊处理,2h后自行恢复正常。结论:米索前列醇在分娩中具有特殊作用,不但可以促进规律宫缩的出现,缩短产程,且具有有效提高新生儿Apgar评分,降低不良反应发生率等优点。
Objective: To investigate the special role of misoprostol in labor. Methods: A retrospective analysis of our hospital from May 2011 to June 2012 admitted to hospital 156 cases of childbirth, were full-term pregnant women, according to the admission has been divided into misoprostol and oxytocin group, 78 cases of misoprostol Group using misoprostol tablets to promote labor, the oxytocin group using oxytocin to promote labor. Results: The total success rate of misoprostol group was 98.72%. The total success rate of oxytocin group was 89.74%. There was significant difference between the two groups (P <0.05). Invalid 9 cases, all by laparotomy. There was no significant difference between the two groups in the incidence of adverse reactions, P> 0.05; the rest of the contrast, there were significant differences, and misoprostol group was significantly better than oxytocin group, P <0.05. As two groups of mild adverse reactions, no special treatment, 2h after the return to normal. Conclusion: Misoprostol has a special role in childbirth. It not only can promote the occurrence of regular contractions and shorten the birth process, but also has the advantages of effectively raising neonatal Apgar score and reducing the incidence of adverse reactions.