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氯丙嗪可并发眼部色素沉着,10余年来,已有不少报道。其它安宁药物是否也有类似作用,意见不一。我们对114名服用治精神病的药物的患者,进行了眼科检查,报道如下。一、检查方法每个患者均查远、近视力,指测眼压,外眼检查,后用3%的新福林散瞳,用裂隙灯检查角膜、前房、晶体、镜检眼底。判定标准: 结膜:球结膜出现黄褐色素双亡为阳性。以“+”表示。角膜:“+”内皮下方有少量棕色素沉着;“++”棕色素沉着,占角膜的1/2;“+++”内皮满布棕色素。前房:前房中有游离色素,以“+”表示。晶体:“+”晶体前囊瞳孔,有盘状白色颗粒沉着,裂隙灯下可辨;“++”前囊有盘状、条状或星状色素沉着,肉眼可辨;“+++”前囊瞳孔有盘
Chlorpromazine can be complicated by eye pigmentation, more than 10 years, there have been many reports. Other tranquility drugs also have similar effects, different views. We conducted an ophthalmological examination of 114 patients taking psychoactive drugs and reported the following. First, the test method Check each patient far, near vision, refers to the measurement of intraocular pressure, the outer eye examination, with 3% of the new Folin mydriasis, with slit lamp examination cornea, anterior chamber, crystals, microscopic examination fundus. Criteria: Conjunctival: conjunctival conjunctival chlamydial double death is positive. To “+” said. Cornea: “+” A small amount of brown pigmentation underlying the endothelium; “++” Brown pigmentation, accounting for 1/2 of the cornea; “+++” The interior is covered with brown pigment. Anterior chamber: free pigment in anterior chamber, with “+” said. Crystal: “+” Crystal anterior capsule pupil, disc-shaped white particles calm, slit lamp discernible; “++” anterior capsule disc, strip or stellate pigmentation, the naked eye can be discerned; “+++” Pre-pupil with disk