红斑狼疮是一种炎症性结缔组织病。发病率女性多于男性,发病年龄多在20～40岁。本病主要分为盘状红斑狼疮和系统性红斑狼疮两个类型,前者主要局限于皮肤,后者可累及全身任何脏器。本病的发生可能是在遗传的基础上,由于感染、日晒、内分泌改变、药物等因素的作用下,使免疫系统功能紊乱所致,主要表现为细胞免疫功能下降,体液免疫功能亢进,产生多种自身抗体,从而导致自身免疫反应,发生组织损伤及一系列表现。 Lupus erythematosus is an inflammatory connective tissue disease. The incidence of more women than men, the incidence of more than 20 to 40 years of age. The disease is divided into two types of discoid lupus erythematosus and systemic lupus erythematosus, the former is mainly confined to the skin, the latter can affect any body organs. The occurrence of this disease may be due to genetic basis, due to infection, sun, endocrine changes, drugs and other factors, the immune system dysfunction caused by the main decline in cellular immunity, humoral immune function hyperactivity, resulting A variety of autoantibodies, leading to autoimmune reactions, tissue damage and a series of manifestations.