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目的 :观察大黄对有机磷农药中毒并发胃肠功能衰竭的疗效。方法 :将 10 7例急性有机磷农药中毒患者随机分为治疗组 ( 5 4例 )、对照组 ( 5 3例 ) ,观察大黄对胃粘膜出血的止血疗效和恢复肠蠕动的疗效。结果 :治疗组与对照组间止血和预防再出血有显著性差异 (P <0 .0 5 ) ,缓解腹胀 ,恢复肠蠕动有显著性差异 (P <0 .0 5 )。结论 :大黄能有效防治有机磷农药中毒并发胃肠功能衰竭 ,促进胃肠蠕动恢复 ,保护胃肠粘膜屏障。
Objective: To observe the effect of rhubarb on organophosphorus pesticide poisoning complicated with gastrointestinal failure. Methods: A total of 107 patients with acute organophosphorus pesticide poisoning were randomly divided into treatment group (54 cases) and control group (53 cases). The curative effect of rhubarb on hemostasis of gastric mucosal hemorrhage and recovery of bowel movement were observed. Results: There was a significant difference between the treatment group and the control group in preventing bleeding and preventing rebleeding (P <0. 05), relieving abdominal distension and recovering peristalsis (P <0.05). Conclusion: Rhubarb can effectively prevent organophosphorus pesticide poisoning complicated by gastrointestinal failure, promote the recovery of gastrointestinal motility and protect the gastrointestinal mucosal barrier.