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目的分析食管癌喉返神经旁淋巴结转移特点及相关因素。方法回顾性分析121例行食管次全切除及现代二野淋巴结清扫术的食管癌患者的临床和病理资料。结果 121例患者中,有喉返神经旁淋巴结转移者28例,清扫喉返神经旁淋巴结370枚,转移淋巴结43枚。喉返神经旁淋巴结转移率为23.1%。肿瘤大小、位置、浸润深度、分化程度、脉管癌栓和食管旁淋巴结转移与喉返神经旁淋巴结转移相关。结论喉返神经旁淋巴结有较高的转移率,对于中上段食管癌、肿瘤较大、低分化及浸润程度较深的患者应重视喉返神经旁淋巴结的清扫。
Objective To analyze the characteristics and related factors of lymph node metastasis of recurrent laryngeal nerve in esophageal cancer. Methods The clinical and pathological data of 121 patients with esophageal cancer who underwent subtotal esophagectomy and modern two-node lymphadenectomy were retrospectively analyzed. Results Among the 121 patients, there were 28 cases of para-lymph node metastasis of the recurrent laryngeal nerve and 370 para-lymph nodes of the recurrent laryngeal nerve and 43 metastatic lymph nodes. The rate of lymph node metastasis around the recurrent laryngeal nerve was 23.1%. Tumor size, location, depth of invasion, degree of differentiation, vascular tumor thrombus, and paraesophageal lymph node metastasis were associated with lymph node metastasis of the recurrent laryngeal nerve. Conclusion There is a high metastasis rate of lymph nodes around the recurrent laryngeal nerve. For patients with upper and middle esophageal cancer, patients with large, poorly differentiated and infiltrated tumors should pay attention to the dissection of the lymph nodes around the recurrent laryngeal nerve.