多发性骨髓瘤(简称骨髓瘤)较为少见,近年来由于检测技术的进步,加之对本病认识的提高,报告的病例有增多趋势,本文报告五例如下。例1 陈××,男,51岁。1966年因尿蛋白(++),诊为慢性肾炎,曾用丙酸睾丸酮等治疗。1970年12月双腿进行性无力,拍片见胸_7病理性骨折,颅骨有散在性骨质疏松区,尿本斯·琼斯蛋白(+),骨髓穿刺证实为骨髓瘤。不久患者出现截瘫,尿失禁。经用N-甲酰溶肉瘤素、环磷酰胺等治疗2个月,大、小便能控制。1972、1973、1974年又三次住院,1974年死于尿毒症。例2 吴××,男,56岁。1975年底发现贫血,血红蛋白6.1g％,红细胞224万。1976年4月,因 Multiple myeloma (referred to as myeloma) is relatively rare, in recent years due to advances in detection technology, combined with the awareness of the disease increased, the reported cases have an increasing trend, the report of five cases as follows. Example 1 Chen × ×, male, 51 years old. 1966 due to urinary protein (++), diagnosed with chronic nephritis, had treated with testosterone propionate. 1970 December legs weakness, film see chest _7 pathological fractures, skull scattered scattered areas of osteoporosis, urinary Jones Jones protein (+), bone marrow puncture confirmed as myeloma. Shortly after the patient appeared paraplegia, incontinence. With N-formylcystein, cyclophosphamide and other treatment for 2 months, large, urine can be controlled. In 1972, 1973, 1974 again in hospital, died of uremia in 1974. Example 2 Wu × ×, male, 56 years old. The end of 1975 found anemia, hemoglobin 6.1g%, 2240000 erythrocytes. April 1976, because