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目的 搜集经药物敏感试验证实的耐多药肺结核 ,探讨耐药肺结核的影像学特点。方法 选取耐多药肺结核 51例为观察组 ,同期不耐药的肺结核病人 46例为对照组。全部病人均有正、侧位胸片 ,部分病人有同期体层或CT片。结果 (1)观察组与对照组相比 ,病变分布差异无显著性意义 (P值均 >0 .0 5)。 (2 )比较病变形态 ,观察组肺内多发结节 (10例 )、播散病灶 (2 3例 )、空腔(9例 )及合并肺毁损 (10例 )多于对照组 ,二者差异有显著性意义 (P <0 0 5)。 (3 )病变的动态变化 ,病变进展观察组多于对照组 ,好转病例观察组少于对照组 ,二者差异有显著性意义 (P <0 0 5)。结论 分析耐多药肺结核的影像表现提示 ,耐多药肺结核具有病变严重 ,活动性明显 ,治疗效果差的特点
Objective To collect multidrug-resistant pulmonary tuberculosis (MDR-TB) confirmed by drug susceptibility test and to explore the imaging features of drug-resistant tuberculosis. Methods Fifty-one patients with multidrug-resistant pulmonary tuberculosis were selected as observation group and 46 non-drug resistant tuberculosis patients as control group. All patients have positive, lateral chest radiograph, some patients have the same period of body layer or CT film. Results (1) There was no significant difference in the distribution of lesions between the observation group and the control group (P> 0.05). (2) Compared with the control group, the lesions in the observation group had multiple nodules (10 cases), disseminated lesions (23 cases), cavity (9 cases) and complicated lung damage (10 cases) There is significant (P <0 05). (3) The dynamic changes of lesions and the progress of lesions were more in the observation group than in the control group, and the improvement cases were less than the control group, the difference was significant (P <0.05). Conclusions The analysis of multidrug-resistant pulmonary tuberculosis manifestations suggest that multidrug-resistant pulmonary tuberculosis has the characteristics of serious disease, obvious activity and poor therapeutic effect