目的　为进一步探讨外阴恶性肿瘤的治疗预后情况。方法　对我院１９７１年～１９９７ 年间收治的外阴恶性肿瘤病人共７１例进行回顾性分析。中位发病年龄５７．９岁；Ⅰ期８ 例、Ⅱ期３２例、Ⅲ期２２ 例、Ⅳ期６例、复发者３ 例；鳞癌５２ 例、恶性黑色素瘤９例、其它类型１０例；手术５４ 例，行腹股沟淋巴结清扫者３５ 例，未清扫者１９例，淋巴结阳性１３ 例占３７．１％ 。结果　总１、３、５、１０、１５ 年生存率分别为８８．６％ 、５６．１％ 、３６．８％ 、２８．０％ 、１６．７％ 。手术病人的各年生存率均明显高于未手术者。淋巴结阳性者的５年生存率显著低于淋巴结阴性者。较早期（Ⅰ、Ⅱ）病人远期（５、１０年）生存率均高于晚期（Ⅲ、Ⅳ），差异显著。结论　手术切除是外阴癌的主要治疗手段，手术方式的选择应个体化，对病期较早淋巴结转移率小的病人可试行单纯外阴切除，术后给予放疗或化疗，但对估计有淋巴结转移可能者，一定要尽早争取淋巴结清扫，术后尽快补充放疗。早期发现、早期诊断、早期治疗对外阴癌的治疗预后尤为重要。外阴复发癌亦应积极创造再治疗机会，如处理得当，可挽救或延长患者生命 Objective To further explore the prognosis of malignant tumors of the vulva. Methods A total of 71 patients with malignant tumors of the vulva treated in our hospital from 1971 to 1997 were analyzed retrospectively. The median age of onset was 57.9 years. There were 8 cases in stage Ⅰ, 32 cases in stage Ⅱ, 22 cases in stage Ⅲ, 6 cases in stage Ⅳ, 3 cases of recurrence, 52 cases of squamous cell carcinoma, 9 cases of malignant melanoma and 10 cases of other types. There were 54 cases underwent surgery, 35 cases underwent inguinal lymph node dissection, 19 cases were not scrutinized, and 13 cases were positive lymph nodes (37.1%). Results The overall 1,3,5,10,15 survival rates were 88.6%, 56.1%, 36.8%, 28.0%, 16.7% respectively. Survival rates of surgical patients were significantly higher than those without surgery. The 5-year survival rate of lymph node positive patients was significantly lower than those with negative lymph nodes. The long-term (5, 10-year) survival rates of patients with earlier (Ⅰ, Ⅱ) were higher than those of patients with advanced stage (Ⅲ, Ⅳ), the difference was significant. Conclusions Surgical resection is the main treatment for vulvar cancer. The choice of surgical method should be individualized. Patients with small lymph node metastasis earlier may be treated with simple vulvectomy and radiotherapy or chemotherapy after surgery. However, it is possible to estimate the possibility of lymph node metastasis Those who must strive for lymph node dissection as soon as possible, postoperative radiotherapy as soon as possible. Early detection, early diagnosis, early treatment of vulvar cancer prognosis is particularly important. Vulvar recurrence cancer should also actively create re-treatment opportunities, such as properly handled, can save or extend patient life