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患者,男,70岁。因慢性支气管炎继发肺内感染住院。二次化验尿糖(++),空腹血糖9.02mmol/L,故给优降糖2.5mg,日2次。服用4天后,患者出现心前区憋闷、心慌,呈阵发性持续3～5分钟,一日发作2～3次。心电图提示:窦性心律,TⅡ、Ⅱ、aVF倒置。经用速效救心丸,硝酸甘油含化等扩冠脉药物均无效,患者继之出现大汗,意识恍惚。复查心电图较前无改变,化验血糖2.58mmol/L,给50％GS100ml静推。患者随即神清,汗止,无任何不适,停用优降糖患者无心前区憋闷发作,心电图正常。讨论优降糖作用快而强,持续时间可达15～24小时,主要经肝脏代谢,24小时内从尿中排出50％。本病例为老年,其代谢及排泄
Patient, male, 70 years old. Chronic bronchitis secondary to pulmonary infection hospitalization. Secondary urine test (++), fasting blood glucose 9.02mmol / L, so give hypoglycemic 2.5mg, 2 times a day. After taking 4 days, patients with precordial feel oppressed, palpitation, paroxysmal 3 to 5 minutes, 2 to 3 episodes on the 1st. ECG tips: sinus rhythm, T Ⅱ, Ⅱ, aVF inversion. Quick-acting heart pills are used, and coronary artery drugs such as nitroglycerin-containing drugs are ineffective. Patients then sweat and unconsciousness. Review ECG unchanged, the test blood glucose 2.58mmol / L, to 50% GS100ml static push. Patients then clear, Khan only, without any discomfort, patients with glyburide discontinuation without presumptive oppressed, electrocardiogram normal. Discussion glyburide fast and strong, lasting up to 15 to 24 hours, mainly by the liver metabolism, urinary excretion of 50% within 24 hours. This case is elderly, its metabolism and excretion