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目的芋螺毒素是一类具有独特药理活性的海洋生物毒素,能高度特异性地作用于各类电压门控和配体门控离子通道及受体,已成为药理学和神经科学研究的一种有力工具和新药开发的重要来源。本文介绍了作用于各种电压门控离子通道的芋螺毒素的研究现状及其应用情况。
Objective Conotoxins, a group of marine biotoxins with unique pharmacological activities, can act on various types of voltage-gated and ligand-gated ion channels and receptors with high specificity and have become a kind of pharmacological and neuroscience research Powerful tools and new sources of drug development. This article describes the research status and application of conotoxins acting on various voltage-gated ion channels.