Preparation and Characterization of Chitosan/β-GP Membranes for Guided Bone Regeneration

来源 :Journal of Wuhan University of Technology(Materials Science | 被引量 : 0次 | 上传用户:jill818
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Bioabsorbable chitosan/β-glycerol phosphate (CS/β-GP) composite membranes were fabricated through a relatively PH neutral and mild sol-gel process for guided bone regeneration (GBR).Their structural properties,morphology,and tensile strength were investigated.FTIR and XRD analyses indicated that there were chemical bonds between the CS andβ-GP.SEM analysis revealed that the CS/β-GP composite membranes had a porous structure both at the surface and in sublayers.Even though the incorporation ofβ-GP in the CS matrix decreased the initial tensile strength of the membrane,the CS/β-GP membranes were still fit for GBR application with their tensile strength of roughly 1MPa.The concentration ofβ-GP was proportional to the pore size and thickness but was inversely proportional to the tensile strength of the CS/β-GP membrane.The present findings indicate that,based on its characteristics,the CS/β-GP composite membrane is a potential bioresorbable membrane for use in guided bone regeneration. Bioirbsorbable chitosan / β-glycerol phosphate (CS / β-GP) composite membranes were fabricated through a relatively PH neutral and mild sol-gel process for guided bone regeneration (GBR). Their structural properties, morphology, and tensile strength were investigated. FTIR and XRD analyzes indicate that there were were chemical bonds between the CS and β-GP. SEM analysis revealed that the CS / β-GP composite membranes had a porous structure both at the surface and in sublayers. Even though the incorporation of β-GP in the CS matrix decreased the initial tensile strength of the membrane, the CS / β-GP membranes were still fit for GBR application with their tensile strength of roughly 1 MPa. The concentration of β-GP was proportional to the pore size and thickness but was inversely proportional to the tensile strength of the CS / β-GP membrane. The present findings indicate that, based on its characteristics, the CS / β-GP composite membrane is a potential bioresorbable membrane for use in guided bone regeneratio tion.
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