目的　评价彩超引导下甲状腺结节粗针穿刺组织学检查的准确性和安全性。方法　以 84例甲状腺结节患者为研究对象 ,在彩超引导下行甲状腺结节粗针穿刺组织学活检并接受手术治疗 ,比较穿刺活检与术后病理结果。结果　 84例全部穿刺成功 ,无并发症发生。穿刺活检与术后病理结果比较 ,总符合率为 92 .86 % ,甲状腺癌的符合率达 10 0 %。结论　彩超引导下甲状腺结节粗针穿刺组织学检查是一种安全、有效的术前确诊手段。 Objective To evaluate the accuracy and safety of histological examination of thyroid nodules under the guidance of color Doppler ultrasound. Methods Totally 84 patients with thyroid nodules were selected as the research objects. Thyroid nodules underwent needle biopsy under the guidance of color Doppler ultrasonography. The biopsy and postoperative pathological results were compared. Results 84 cases of all successful puncture, no complications. The total biopsy and postoperative pathological results were 92.86%, and the coincidence rate of thyroid cancer was 100%. Conclusions Color-guided ultrasonography guided thyroidectomy is a safe and effective method for the diagnosis of thyroid nodules.