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目的探讨无创性通气治疗慢性阻塞性肺疾病(COPD)并Ⅱ型呼吸衰竭的临床应用价值。方法对35例慢性阻塞性肺疾病(COPD)并Ⅱ型呼吸衰竭患者采用呼吸机,观察治疗前后血气分析的pH、PaO2、PaCO2、SaO2指标变化。结果无创性通气治疗后PaO2、SaO2均明显升高PaCO2降低,pH明显改善,经比较差异均有统计学意义(P<0.01)。结论呼吸机经口鼻面罩正压通气治疗COPD并Ⅱ型呼吸衰竭效果满意,未发现明显并发症,值得临床推广应用。
Objective To investigate the clinical value of noninvasive ventilation in the treatment of chronic obstructive pulmonary disease (COPD) and type Ⅱ respiratory failure. Methods Ventilator was used in 35 patients with chronic obstructive pulmonary disease (COPD) and type Ⅱ respiratory failure. The changes of pH, PaO2, PaCO2 and SaO2 in blood gas analysis before and after treatment were observed. Results After non-invasive ventilation, PaO2 and SaO2 were significantly increased PaCO2 decreased, pH significantly improved, the difference was statistically significant (P <0.01). Conclusion Ventilator nasal mask positive pressure ventilation for COPD and type Ⅱ respiratory failure with satisfactory results, no significant complications, it is worthy of clinical application.