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目的:探索经内外括约肌间肛门内括约肌侧切术（ILIS）治疗慢性肛裂的疗效。方法:对2018年2—6月宁波大学医学院附属医院25例慢性肛裂患者采用经内外括约肌间肛门内括约肌侧切术治疗，分析其愈合时间、术后1、3、5 d疼痛评分、Wexner评分和肛门直肠压力，评价此手术的有效性。结果:所有患者均手术顺利，其中24例患者慢性肛裂手术切口Ⅰ级愈合，愈合时间为（14.66 ± 5.63）d，1例患者为Ⅱ级愈合，术后1、3和5 d疼痛评分分别为（2.32 ± 0.82）、（1.66 ± 0.74）和（1.22 ± 0.63）分，没有患者发生肛门失禁，肛门失禁评分为0分。结论:经内外括约肌间肛门内括约肌侧切术是治疗慢性肛裂的一种微创、疼痛轻、安全有效的手术方式。“,”Objective:To describe a new technique for chronic anal fissure surgery aimed at minimal invasion and reducing pain, and to evaluate the preliminary results concerning non-healing and intact anal function.Methods:A prospective observational study in twenty-five chronic anal fissure patients treated by Intersphincteric Lateral Internal Sphincterotomy (ILIS) technique from February to June 2018 in the Affiliated Hospital of Medical School of Ningbo University were conducted.Results:Chronic anal fissure in twenty-five patients healed primarily (96%, 24/25). There was one non-healing case. The mean healing time was(14.66 ± 5.63) d. Pain scores of 1, 3 and 5 d after surgery were (2.32 ± 0.82), (1.66 ± 0.74), (1.22 ± 0.63) scores. None had disturbance in clinical anal continence. Wexner score was 0.Conclusions:The early outcome of the ILIS technique is quite impressive. This technique is minimally invasive, with shorter healing time and less pain. It has the potential to become a viable option for chronic anal fissure surgery.