病例:患儿女,1天,因呼吸浅促1天入院。系第一胎第一产,胎龄40+4周,顺产娩出,羊水Ⅲ°污染,阿氏评分9-10-10分。生后不久出现呼吸浅促,拍胸片报告肺炎、双锁骨骨折转入新生儿病房(图1)。母孕期健康,第一胎人流。父母非近亲结婚,否认家族中有遗传病病史。入院查体:体温36·5,心率 Case: Children, 1 day, due to shortness of breath 1 day admission. Department of the first birth of the first child, gestational age 40 + 4 weeks, delivered by natural delivery, amniotic fluid Ⅲ ° pollution, Ash scores 9-10-10 points. Shortness of breath shortly after birth, pneumothorax report pneumothorax, double clavicle fracture into the neonatal ward (Figure 1). Mother during pregnancy, the first child flow. Parents marry non-relatives, denied the family history of genetic disease. Admission examination: body temperature 36.5, heart rate