为了从基因水平探讨肺癌影像学表现的分子生物学基础，利用免疫组化技术及计算机图象系统测定手术病理证实之３３例肺癌标本中癌基因ｅｒｂＢ－２，ｂｃｌ－２的表达水平，系统分析其表达水平与影像学表现的相关性。结果显示肺癌的某些影像学征象如肿块大小、三级支气管受累、胸膜受侵及肺门纵隔淋巴结转移均与其癌基因ｅｒｂＢ－２、ｂｃｌ－２的表达水平密切相关，而且这两类基因的表达对其影像学征象的影响呈现相互抑制的关系 In order to explore the molecular biology basis of lung cancer imaging at the gene level, the expression of oncogene erbB-2 and bcl-2 in 33 cases of lung cancer specimens confirmed by surgery and pathology was analyzed by immunohistochemistry and computer image system. The correlation between the expression level and imaging findings. The results showed that some imaging features of lung cancer such as tumor size, grade 3 bronchial involvement, pleural invasion and hilar mediastinal lymph node metastasis were closely related to the expression of oncogene erbB-2 and bcl-2, The expression of its imaging signs showed a mutually inhibitory relationship