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目的:探讨血小板参数——血小板数量(PLT)、平均血小板体积(MPV)、血小板体积分布宽度(PDW)等在肾综合症出血热(HFRS)患者中的变化及其临床意义。方法:选取HFRS患者53例和正常对照组30名,采用F-820血细胞分析仪测定血小板参数PLT、MPV、PDW,并用统计学方法(t检验)对数据进行处理。结果:HFRS患者PLT明显低于正常对照组(P<0.01),而MPV、PDW明显高于正常对照组(P<0.01)。结论:血小板参数PLT、MPV、PDW在辅助诊断HFRS中有一定临床价值。
Objective: To investigate the changes and clinical significance of platelet parameters such as platelet count (PLT), mean platelet volume (MPV) and platelet volume distribution width (PDW) in patients with hemorrhagic fever with renal syndrome (HFRS). Methods: Fifty-three patients with HFRS and 30 normal controls were enrolled in this study. Platelet parameters PLT, MPV and PDW were measured by F-820 hematology analyzer. Data were processed by statistical methods (t-test). Results: The PLT of HFRS patients was significantly lower than that of the normal control group (P <0.01), while the MPV and PDW were significantly higher than those of the normal control group (P <0.01). Conclusion: Platelet parameters PLT, MPV and PDW have some clinical value in the diagnosis of HFRS.