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目的观察比索洛尔联合福辛普利治疗肾综合征出血热并急性肾功能衰竭(肾衰)的疗效。方法 86例肾综合征出血热并急性肾功能衰竭患者,随机分为治疗组(44例)及对照组(42例)。两组患者的综合性治疗措施相同,治疗组加服比索洛尔与福辛普利。比较两组患者的治疗效果。结果治疗组少尿期持续时间、多尿期来临病日、住院时间较对照组短,肾功能改善及预后较对照组优,并发症发生较对照组少,比较差异均有统计学意义(P<0.05)。结论比索洛尔联合福辛普利治疗肾综合征出血热并急性肾功能衰竭疗效确切,服用方便,不良反应少,值得推广。
Objective To observe the efficacy of bisoprolol combined with fosinopril in the treatment of hemorrhagic fever with renal syndrome and acute renal failure (renal failure). Methods 86 patients with hemorrhagic fever with renal syndrome and acute renal failure were randomly divided into treatment group (n = 44) and control group (n = 42). The two groups of patients with the same treatment, the treatment group plus bisoprolol and fosinopril. The treatment effect of two groups of patients was compared. Results The duration of oliguria, the onset date of polyuria, the length of stay in hospital were shorter than those in control group. The improvement of renal function and prognosis were better than those in control group. The incidence of complications was lower than that in control group (P <0.05). Conclusions Bisoprolol combined with fosinopril is effective in treating hemorrhagic fever with renal syndrome and acute renal failure. It is convenient to take and has few adverse reactions and is worth popularizing.