阿米替林能引起中毒性谵妄,主要由于中枢抗胆碱能作用,在临床应用时不可忽视,现报告我院遇到的一例。患者、男、58岁、1988年3月27日入院,诊断抑郁症。给予阿米替林治疗,自100mg/日渐增至300mg/日;半月后抑郁症状基本消失。于5月28日夜间患者惊恐喊叫,企图冲出病室,并有走错门,睡错床,随地小便,把大 Amitriptyline can cause toxic delirium, mainly due to central anticholinergic effects, can not be ignored in clinical applications, are reported in our hospital encountered an example. Patient, male, 58 years old, admitted to hospital on March 27, 1988 to diagnose depression. Given amitriptyline treatment, from 100mg / day to 300mg / day; half the symptoms of depression disappeared. In the night of May 28, patients screamed in an attempt to rush out of the ward, and the wrong door, sleep bed, urinate anywhere, large