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目的了解河南省病毒性脑炎的病原种类及其分布。方法采用ELISA方法对2005年我省临床诊断为病毒性脑炎患者的急性期血清和脑脊液标本检测病毒特异性IgM抗体。结果209例患者中的193例(92.3%)检测出病毒特异性IgM抗体,构成顺序依次为柯萨奇病毒、埃可病毒、腮腺炎病毒、单纯疱疹病毒、乙脑病毒、EB病毒和水痘-带状疱疹病毒。结论肠道病毒、腮腺炎病毒、单纯疱疹病毒、乙脑病毒是我省病毒性脑炎的主要病原。
Objective To understand the etiological species and distribution of viral encephalitis in Henan Province. Methods Serum and cerebrospinal fluid (CSF) samples were collected from patients with viral encephalitis in our province in 2005 for the detection of virus-specific IgM antibodies. Results Ninety-nine (92.3%) of the 209 patients detected virus-specific IgM antibodies in the order of Coxsackie, Echovirus, Mumps, Herpes simplex, Encephalitis, Epstein-Barr virus and Varicella- Herpes zoster virus. Conclusions Enterovirus, mumps virus, herpes simplex virus and Japanese encephalitis virus are the main pathogens of viral encephalitis in our province.