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缺氧诱导因子-1(hypoxia-inducible factor-1,HIF-1)是在研究缺氧诱导的红细胞生成素(erythropoietin,EPO)的基因表达时发现的一种DNA结合蛋白,其分布和作用十分广泛,目前已确定的靶基因已有130多种,且这些基因编码的蛋白参与血
Hypoxia-inducible factor-1 (HIF-1) is a DNA-binding protein found in the gene expression of hypoxia-induced erythropoietin (EPO), and its distribution and function are quite There are more than 130 target genes that have been identified so far, and the proteins encoded by these genes are involved in blood