X综合征是指临床上有典型劳力型心绞痛 ,运动试验阳性而冠状动脉造影正常的患者[1 ] 。国外已有资料证实 ,利尿剂可防止硝酸盐耐受的发生 ,并有独立的抗心绞痛作用[2～ 4] 。2 0 0 0～ 2 0 0 1年 ,我院收治X综合征患者 2 1例 ,采用利尿剂治疗 ,旨在探讨其对X综合征患者最大氧耗 Syndrome X is clinically typical of patients with angina pectoris, motor test positive patients with normal coronary angiography [1]. Foreign data have confirmed that diuretics can prevent the occurrence of nitrate tolerance, and an independent anti-angina pectoris [2 ~ 4]. From 2000 to 2001, 21 patients with syndrome X in our hospital were treated with diuretics, in order to investigate their maximum oxygen consumption in patients with syndrome X