论文部分内容阅读
白细胞介素-4(IL-4)是由 CD~(3+),淋巴细胞分泌的一种多效性淋巴因子,它能抑制白细胞介素-2(IL-2)诱导的 T 细胞繁殖及其杀伤活性,促进已被抗原激活的 T 细胞的繁殖,并增加被 IL-2激活的大颗粒淋巴细胞非特异性溶解活性。人们用 IL-4这些特点治疗晚期肿瘤患者。作者曾报道,联合应用 IL-2和 IL-4有治疗晚期肿瘤的作用,但单独应用 IL-4无此作用。本文报道 IL-4诱发胃窦溃疡或糜烂。观察结果表明,免疫制剂如 IL-2和 IL-4能改变胃粘膜的完整性。
Interleukin-4 (IL-4) is a pleiotropic lymphokine secreted by CD3+ lymphocytes that inhibits IL-2 induced T cell proliferation and Its killing activity promotes the proliferation of antigen activated T cells and increases the non-specific lytic activity of IL-2 activated large granular lymphocytes. People use the characteristics of IL-4 to treat advanced cancer patients. The authors have reported that the combined use of IL-2 and IL-4 has the effect of treating advanced tumors, but IL-4 alone has no such effect. This article reports IL-4 induced antral ulcer or erosion. Observations have shown that immune agents such as IL-2 and IL-4 can change the integrity of the gastric mucosa.