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目的 观察早产合并胎膜早破(Premature Ia-bov complicated with premature rupture of mem-brane,PPROM)的诊治情况。方法 对432例PPROM进行回顾性分析,结果 66.7％的PPROM有易发因素存在。孕周<34周围生儿病死率高于≥34周,有极显著性差异(P<0.01),<34周新生儿窒息率高于≥34周者,有显著性差异(P<0.01)。<34周者呼吸窘迫综合症(ROS)明显增加,超过34周围生儿存活率明显增高。结论 对于孕28～34周PPROM宜采取期待疗法,以减少新生儿合并症的发生。对孕周小者,尽量延长孕周至30周以上,可降低新生儿死亡率。
Objective To observe the diagnosis and treatment of Premature Ia-bov complicated with premature rupture of mem-brane (PPROM). Methods 432 cases of PPROM were retrospectively analyzed, the results of 66.7% of the PPROM prone factors exist. There was a significant difference (P <0.01) in the mortality rate of children with gestational age <34 weeks and higher than 34 weeks (P <0.01). The rate of neonatal asphyxia was lower than 34 weeks after 34 gestational weeks (P <0.01). <34 weeks of respiratory distress syndrome (ROS) was significantly increased, more than 34 weeks survival rate was significantly higher. Conclusions For PPROM at 28-34 weeks of pregnancy, expectant therapy should be taken to reduce the incidence of neonatal complications. Small gestational weeks, try to extend the gestational age to more than 30 weeks, can reduce neonatal mortality.