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目的研究HCG注射后不同时间(42h与40h)行短时授精(3h)对体外受精胚胎移植(IVF-ET)受精率、卵裂率及临床妊娠率的影响。方法对郑州大学附属洛阳中心医院生殖中心实施IVF-ET的962例患者新鲜周期进行回顾性总结和分析,根据HCG注射后不同时间授精分为2组(A组:2009年3月-2012年3月HCG后42h授精440例;B组:2012年4月-2013年9月HCG后40h授精共522例。对两组平均年龄、受精率、卵裂率及临床妊娠率之间的关系进行分析。结果两组年龄、受精率和卵裂率无差异,但临床妊娠率具有显著统计学差异。结论 HCG后不同时间短时授精将影响IVF-ET胚胎发育及临床妊娠率。
Objective To investigate the effect of short-term insemination (3h) at different time (42h and 40h) after HCG injection on fertilization rate, cleavage rate and clinical pregnancy rate of IVF-ET. Methods A total of 962 freshmen who underwent IVF-ET in the Reproductive Center of Luoyang Central Hospital Affiliated to Zhengzhou University were retrospectively reviewed and divided into two groups according to different time after HCG injection (Group A: March 2009-March 2012 42 months after HCG fertilization 440 cases; Group B: April 2012 - September 2013 40 h after HCG insemination of a total of 522 cases.Analysis of the relationship between the two groups, the average age, fertilization rate, cleavage rate and clinical pregnancy rate Results There was no difference in age, fertilization rate and cleavage rate between the two groups, but the clinical pregnancy rate had significant statistical difference.Conclusion Short-term insemination at different time after HCG will affect IVF-ET embryo development and clinical pregnancy rate.