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对于伴有AFP升高的非癌性肝病及AFP阳性的原发性肝癌患者,仅测定其血清AFP总量往往难以区分良、恶性肝病。作者已报道AFP分子糖链结构改变与细胞处于不同的病变状态相关,对鉴别诊断及早期诊断畸胎癌和良恶性肝病提供了实
For patients with non-cancerous liver disease and AFP-positive primary liver cancer with elevated AFP, it is difficult to distinguish between benign and malignant liver disease by measuring only the total amount of serum AFP. The authors have reported that the structural changes in the sugar chain of AFP are related to the different pathological states of the cells, and provide a basis for differential diagnosis and early diagnosis of teratocarcinoma and benign and malignant liver diseases.