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目的了解梅尼埃病与自身免疫之间的关系。方法测试了30例正常人和30例梅尼埃病患者血清中的非特异性免疫球蛋白（IgG、IgM和IgA），补体（C3和C4），以及抗Ⅱ型胶原抗体。结果梅尼埃病患者血清中非特异性IgG、IgM和IgA以及C3和C4均在正常范围；而患者中53．3％的抗Ⅱ型胶原抗体IgG明显增高，在正常对照组的血清中抗Ⅱ型胶原抗体均不增高。结论自身免疫反应可能是该病的原因之一。
Objective To understand the relationship between Meniere’s disease and autoimmunity. Methods Serum nonspecific immunoglobulins (IgG, IgM and IgA), complement (C3 and C4), and anti-type II collagen antibodies were tested in 30 normal and 30 Meniere’s disease patients. Results Serum non-specific IgG, IgM and IgA and C3 and C4 were all within the normal range in Meniere’s disease patients. 53.3% of the patients with anti-type II collagen IgG were significantly increased in serum, Type collagen antibodies are not increased. Conclusion The autoimmune reaction may be one of the causes of the disease.