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目的:解决女贞片压片过程中的松片、裂片问题。方法:在女贞片制粒过程中,加入适量炼蜜作黏合剂,并控制颗粒含水量在4%～6%[1],再行压片,并按照片剂的质量要求进行质量检查。结果:在女贞片的制备过程中加入适量炼蜜且控制颗粒含水量后,提高了颗粒的可压性,解决了以往压制时出现的松片、裂片问题,并且保证了所制片剂的质量。结论:采用该方法降低了颗粒弹性,使其具备良好的可压性,且操作简便易行,所制片剂质量可控。
Objective: To solve the problem of loose loins and lobes in the process of privet lozenges. Method: During the process of privet tablet granulation, adding appropriate amount of honey as binder and controlling the water content of granule to 4% ~ 6% [1], then tabletting and quality checking according to the quality requirements of tablets. Results: Addition of proper amount of honey and the control of water content during the preparation of the privet patch increased the compressibility of the granules, solved the problems of loose patches and splits in the past pressing, and ensured that the quality. Conclusion: This method can reduce the elasticity of granule, make it have good compressibility, and the operation is simple and easy. The quality of the prepared tablets can be controlled.