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目的:观察并讨论慢性HBV感染者肝脏病理与ALT、性别及年龄的临床关系分析,为临床治疗提供依据。方法:选取2014年12月~2015年12月来我院治疗的136例慢性HBV感染者进行回顾性分析,对所有患者行穿刺病理诊断、血清学检查,分析炎症和ALT、性别及年龄等因素关系。结果:经分析得知,不同炎症分级的患者在年龄、ALT的生化指标上存在显著差异(P>0.05),不同炎症分级的患者性别、HBV DNA无显著差异(P>0.05)。结论:临床慢性HBV感染者年龄>30岁在一定程度存在肝组织病理学异常,需尽早明确诊断,临床可积极行肝穿刺活检,以期掌控抗病毒感染的最佳的时机,帮助患者肝功能实现尽早恢复。
Objective: To observe and discuss the relationship between liver pathology and ALT, sex and age in patients with chronic HBV infection and provide the basis for clinical treatment. Methods: A retrospective analysis of 136 patients with chronic HBV infection treated in our hospital from December 2014 to December 2015 was performed. All the patients were examined by biopsy, serological examination, inflammation and ALT, sex and age relationship. Results: According to the analysis, there were significant differences in the biochemical indexes of ALT between different grades of inflammation (P> 0.05). There was no significant difference in gender and HBV DNA between different grades of inflammation (P> 0.05). Conclusion: Chronic HBV infection in patients with chronic hepatitis B (HBV) infection has liver histopathology to some extent. Diagnosis should be made as soon as possible. Liver biopsy can be actively performed in clinic so as to control the optimal timing of antiviral infection and help patients achieve liver function Recovery as soon as possible.