细胞凋亡是机体正常发育过程中普遍存在的生命现象，神经系统的发育也不例外。细胞凋亡与细胞增殖同等重要，二者的动态平衡保证了神经系统的正常发育。近年来研究发现，细胞凋亡受到细胞内多种基因以及细胞外因素的调控。本文就细胞凋亡的生物学特征、基因调控及其与细胞周期的关系等几方面进行了综述 Apoptosis is a common life phenomenon in the normal development of the body, the development of the nervous system is no exception. Apoptosis and cell proliferation are equally important, the dynamic balance of the two to ensure the normal development of the nervous system. In recent years, studies have found that apoptosis is regulated by a variety of genes in the cell and extracellular factors. In this paper, the biological characteristics of apoptosis, gene regulation and its relationship with the cell cycle were reviewed