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实验在23只经乌拉坦麻醉的家兔上进行。微量注射L-谷氨酸钠引起潮气量(V_T)抑制的点集中在延髓腹外侧网状巨细胞核腹外侧分和外侧网状核的内侧分,在闩前2mm和1mm水平,V_T分别减小37.3±9.9％和22.9±8.1％(p<0.01)。血压的变化包括升压和降压。在闩前2mm,升压点(17)多于降压点(12);而在闩前1mm,降压点(16)明显多于升压点(5)。两个水平反应点分布的差异具有显著性(p<0.05)。于上述谷氨酸钠敏感区微量注射利多卡因后,由加压延髓腹侧引起的呼吸和血压效应明显减弱或完全消失,提示这一部位可能是压力敏感区感受细胞所在。
The experiment was performed on 23 rabbits anesthetized with urethane. Microinjection of L-glutamate induced a decrease in tidal volume (V_T) in the medial part of the reticular and medial reticular nucleus of the reticular ventrolateral medulla in the medulla oblongata, with V_T decreased at 2 mm and 1 mm pre-latch, respectively 37.3 ± 9.9% and 22.9 ± 8.1% (p <0.01). Changes in blood pressure include blood pressure and blood pressure. At 2 mm before the latch, the boost point (17) is more than the buck point (12); while at 1 mm before the latch, the buck point (16) is significantly more than the boost point (5). The differences in the distribution of the two horizontal response points were significant (p <0.05). After the micro-injection of lidocaine in the sensitive area of glutamate, the effects of respiration and blood pressure caused by the ventral medulla significantly decreased or completely disappeared, suggesting that this site may be the sensing area of cells in the pressure sensitive area.