论文部分内容阅读
目的观察小剂量螺内酯联合美托洛尔对慢性心力衰竭患者心肌重构的影响。方法将120例慢性心力衰竭患者随机分为治疗组和对照组各60例,均予常规抗心衰治疗,治疗组加服小剂量螺内酯联合美托洛尔,疗程12周,观察治疗前后心功能改善和超声指标的变化。结果治疗组治疗后其心功能改善、超声指标均较对照组有明显改善(P<0.05)。结论小剂量螺内酯联合美托洛尔治疗能显著改善慢性心力衰竭患者的心功能及抑制心肌重构。
Objective To observe the effect of low dose spironolactone combined with metoprolol on cardiac remodeling in patients with chronic heart failure. Methods 120 cases of chronic heart failure were randomly divided into treatment group and control group, 60 cases were treated with conventional anti-heart failure, the treatment group plus a small dose of spironolactone combined with metoprolol, the course of 12 weeks, before and after treatment to observe the cardiac function Improvement and changes in ultrasound index. Results After treatment, the cardiac function of the treatment group improved and the ultrasound indexes were significantly improved compared with the control group (P <0.05). Conclusion Low-dose spironolactone combined with metoprolol can significantly improve cardiac function and myocardial remodeling in patients with chronic heart failure.