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按照维生素B_(12)与叶酸的不同供给量。将大鼠60只,分为3组。第1组供给不足,第2组接近正常,第3组较为充裕。饲养四周后,第1组氮摄入量,尿中总氮与脲氮低于第2组与第3组。口服50mgL—组氨酸的负荷试验可使各组尿氮增加量超过负荷量,并使第1组尿中氨基氮与氨氮增加。照射700拉德后氮摄入量减少系食欲不振所致。摄食量减少或辐射损伤可使维生素B_(12)与叶酸营养不足时尿中氨基氮与氨氮排出量增加。增高维生素B_(12)与叶酸供给量不仅可消除组氨酸负荷、摄食量减少或辐射损伤对氮代谢的影响,而且还可有所改善。
According to the different supply of vitamin B_ (12) and folic acid. Sixty rats were divided into three groups. Group 1 lack of supply, Group 2 close to normal, Group 3 more abundant. Four weeks after feeding, the nitrogen intake of group 1, the total nitrogen and urea nitrogen in urine were lower than those in group 2 and group 3. Oral 50mgL-histidine load test can increase the amount of urine nitrogen in each group over the load, and the first group of urine amino nitrogen and ammonia increased. Irradiation Irradiation Irradiation after 700 LAD Decreased loss of appetite. Reduced food intake or radiation damage can make vitamin B_ (12) and folic acid undernutrition, urinary amino nitrogen and ammonia nitrogen emissions increased. Increasing vitamin B 12 and folic acid supply can not only reduce the effect of histidine load, food intake, or radiation damage on nitrogen metabolism, but also improve the metabolism of vitamin B 12.