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目的：观察脑动脉硬化症血浆TNF－α、NO与肾虚证、血瘀症及肾虚血瘀证的相关性。方法：抽取患者空腹静脉血，离心取血清，放免法检测TNF－α含量，酶法检测NO含量，采用F检验和q检验进行统计分析。结果：血瘀证、肾虚血瘀证患者血清TNF－α含量高于肾虚证患者（P均小于0．01），而血瘀证与肾虚血瘀证比较差异无统计学意义（P＞0.05）。肾虚证、肾虚血瘀证患者血清NO含量高于血瘀证患者（P＜0．01），而肾虚证、肾虚血瘀证比较差异无统计学意义（P＞0.05）。结论：脑动脉硬化症血瘀证与血清TNF－α水平相关，而脑动脉硬化症肾虚证与血清NO水平相关。
Objective: To observe the correlation between plasma TNF-α, NO and kidney deficiency syndrome, blood stasis syndrome and kidney-deficiency and blood stasis syndrome in cerebral arteriosclerosis. Methods: The fasting venous blood was collected from patients. The serum was taken out by centrifugation. The content of TNF-α was detected by radioimmunoassay. The content of NO was detected by enzymatic method. F-test and q-test were used for statistical analysis. Results: The serum levels of TNF-α in patients with blood stasis syndrome and kidney-yang blood stasis syndrome were significantly higher than those with kidney deficiency syndrome (all P <0.01), but there was no significant difference between them (P> 0.05) . Kidney deficiency syndrome, kidney deficiency blood stasis syndrome patients with serum NO levels higher than those of patients with blood stasis (P <0.01), and kidney deficiency syndrome, kidney deficiency and blood stasis syndrome was no significant difference (P> 0.05). Conclusion: The blood stasis syndrome of cerebral arteriosclerosis is related to the level of serum TNF-α, while the deficiency of kidney-deficiency syndrome of cerebral arteriosclerosis is related to the serum NO level.