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丁型肝炎病毒(HDV或称δ因子)是一种缺陷RNA病毒,仅在乙型肝炎病毒(HBV)感染过的患者体内才能复制。作者报告3例慢性HBV感染(病程3～6年)发生HDV重叠感染后1～7个月内,循环中的HBsAg均消失。随后,出现HDV抗体,临床恢复健康,转氨酶正常,且其中2例出现抗-HBs。例1:31岁男性同性恋者,1978年6月首次发现:HBsAg阳性。1979年8月转氨酶轻度异常,HBeAg和血清HBV DNA强阳性。1980年12月转氨酶升到正常5倍以上,
Hepatitis D virus (HDV or delta-factor) is a defective RNA virus that replicates only in patients with hepatitis B virus (HBV) infection. The authors report circulating HBsAg disappeared within 1 to 7 months after three HDV infections (course of 3 to 6 years) in patients with chronic HBV infection. Subsequently, HDV antibodies appeared, returned to normal clinics, and aminotransferases were normal, and two of them showed anti-HBs. Example 1: Male homosexual 31 years old, first discovered in June 1978: HBsAg positive. August 1979 mild transaminase abnormalities, HBeAg and serum HBV DNA strongly positive. December 1980 aminotransferase rose to more than 5 times normal,