Developmental process of the arcuate fasciculus from infancy to adolescence:a diffusion tensor imagi

来源 :中国神经再生研究(英文版) | 被引量 : 0次 | 上传用户:JoshuaSiu
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We investigated the radiologic developmental process of the arcuate fasciculus (AF) using subcomponent diffusion tensor imaging (DTI) analysis in typically developing volunteers. DTI data were acquired from 96 consecutive typically developing children, aged 0–14 years. AF subcomponents, including the posterior, anterior, and direct AF tracts were analyzed. Success rates of analysis (AR) and fractional anisotropy (FA) values of each subcomponent tract were measured and compared. AR of all subcomponent tracts, except the posterior, showed a signiifcant increase with aging (P < 0.05). Subcomponent tracts had a speciifc de-velopmental sequence: First, the posterior AF tract, second, the anterior AF tract, and last, the direct AF tract in identical hemispheres. FA values of all subcomponent tracts, except right direct AF tract, showed correlation with subject’s age (P < 0.05). Increased AR and FA values were observed in female subjects in young age (0–2 years) group compared with males (P < 0.05). The direct AF tract showed leftward hemi-spheric asymmetry and this tendency showed greater consolidation in older age (3–14 years) groups (P <0.05). These ifndings demonstrated the radiologic developmental patts of the AF from infancy to adoles-cence using subcomponent DTI analysis. The AF showed a speciifc developmental sequence, sex difference in younger age, and hemispheric asymmetry in older age.
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